Kanna Happy Calming Extract - 1 gram: serenity meets contentment
Discover the gentle side of Kanna with the Happy Calming extract, a refined crystalline extract that brings together serenity and contentment. This product, standardized to mannitol, offers a subtle approach to Kanna by using a lower concentration of mesembrine than the Krystal Ultimate extract. With a total alkaloid content of approximately 5.4% and a mesembrine content of about 3%, this extract is designed for those who prefer a milder experience.
A balanced alkaloid profile
The Kanna Happy Calming extract is characterized by a carefully balanced alkaloid profile:
Total Alkaloids: 5.4%
- Mesembrine: approximately 60%
- Mesembrenone: approximately 20%
- Δ7-Mesembrenone: approximately 15%
This composition provides a harmonious experience that is both calming and joyful, without the intensity of higher Mesembrine concentrations. It is the perfect choice for those seeking a subtle yet satisfying approach to Kanna.
Usage and Versatility
The Happy Calming extract is easy to use and can be applied in various ways, depending on personal preference and experience. Start with a small amount to gauge your personal response and adjust the dosage as needed. Thanks to its fine crystalline structure, this extract is both easy to dose and consume, making it an accessible option for both new and experienced users.
Why choose Kanna Happy Calming Extract?
Choose Kanna Happy Calming Extract if you:
- Are looking for an extract with a milder mesembrine content.
- Value the quality and purity of your Kanna extract.
- Want an extract that offers a calming and joyful experience without the intensity of stronger varieties.
Caution advised
Although this extract offers a milder alternative, it is important to use it with care and to take personal sensitivity and experience into account. This product is particularly suitable for those seeking a subtle introduction to Kanna or who prefer a gentle experience.
Kanna contains active compounds such as mesembrine, mesembrenone, mesembrenol, and tortuosamine, with mesembrine acting as a selective serotonin reuptake inhibitor (SSRI). It is important not to combine Kanna with other SSRIs or MAO inhibitors to prevent adverse interactions.
The Kanna Happy Calming Extract - 1 gram invites you to explore the calming and joyful aspects of Kanna in a fine crystalline form. Available at Dutch-Smart.nl, this extract promises a serene and satisfying experience for anyone who wants to experience the true essence of Kanna in a subtle way.
Alkaloid Profile of Kanna Happy Calming
Kanna Happy Calming contains 5.4% total alkaloids. According to the label, about 60% of those is mesembrine, 20% mesembrenone and 15% Δ7-mesembrenone. That comes down to roughly 3.2% mesembrine in the extract, less than in Krystal Ultimate.
- Total alkaloids: 5.4%
- Mesembrine: about 60% of the alkaloid profile (roughly 3.2% of the extract)
- Mesembrenone: about 20% of the alkaloid profile
- Δ7-mesembrenone: about 15% of the alkaloid profile
- Carrier: D-mannitol
- Contents: 1 gram
What Does Each Alkaloid Do?
In lab studies, the alkaloids in kanna (Sceletium tortuosum) act on two targets: the serotonin transporter and the enzyme PDE4. Each alkaloid does so to a different degree, which explains why extracts with a different profile feel different.
±60%Mesembrineof the alkaloid profile
The main alkaloid in kanna. In lab studies (in vitro), mesembrine binds very strongly to the serotonin transporter (Ki 1.4 nM). It has little effect on the enzyme PDE4. Users mostly describe extracts high in mesembrine as euphoric, warm and sociable.
Euphoria5 out of 5
Relaxation3 out of 5
Energy and clarity2 out of 5
±20%Mesembrenoneof the alkaloid profile
Lab studies (in vitro) show two targets: the serotonin transporter (Ki 27 nM, weaker than mesembrine) and the enzyme PDE4 (IC50 0.47 µM), where it is the strongest of the kanna alkaloids. Users often find extracts with more mesembrenone fresher and more energetic.
Euphoria2 out of 5
Relaxation2 out of 5
Energy and clarity4 out of 5
±15%Δ7-mesembrenoneof the alkaloid profile
Chemically close to mesembrenone and a natural part of the alkaloid profile of Sceletium tortuosum. Users describe extracts high in Δ7-mesembrenone as calmer and more physically relaxed.
Euphoria2 out of 5
Relaxation5 out of 5
Energy and clarity1 out of 5
Scores based on user reports.
Effect Profile of This Extract
Weight the scores of the three alkaloids by their share in this extract and you get this profile:

Euphoria4 out of 5
Relaxation3 out of 5
Energy and clarity2.5 out of 5
Indicative profile, calculated from the alkaloid ratio on the label and the action of each alkaloid. This is not medical information. How you experience kanna varies by person, dose and setting.
Euphoria remains the main note, but with 15% Δ7-mesembrenone, relaxation gets more room than in the stronger extracts. Want to shift the balance further towards calm? Take a look at Kanna Merry Stony. Browse all options in our kanna category.
Dosage According to the Label
Use no more than 25 mg at a time. At 5.4% total alkaloids, 25 mg contains about 1.35 mg of alkaloids, of which roughly 0.8 mg is mesembrine. Weigh it with a scale that reads to 0.001 gram and start lower if this extract is new to you.
Never combine kanna with SSRIs, MAO inhibitors or other antidepressants: mesembrine acts on the serotonin system, so the effects can stack dangerously. Don't use it with alcohol or drugs, or if you have mental health issues. Adults 18+ only.
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